Yes, but you first need to use the SRAM AXS App to assign an enhanced shift mode (Sequential or Compensating).
See our AXS Mobile App section for app tutorials.
Following this, you can then toggle between full manual shifting and the preselected enhanced shift mode by pressing the AXS buttons on the shift paddles. This can even be done while riding!
Tech Tip | Enhanced shifting mode will return to its default "off" setting anytime the system is re-paired. So remember to re-enable it after pairing the components to one another.