Does AXS Web work with Shimano Di2 shifting? SRAM AXS Web will work with Shimano Di2 shifting. Be sure to pair your components to the headunit that is linked to AXS Web. Related articles Does AXS Web work with Strava? Can I fit SRAM Eagle AXS™ to any mountain bike and what are the compatibility requirements for Eagle AXS™? Does AXS Web work with any power meter? What is AXS Web? Does AXS Web work with original SRAM RED eTap?