Can I set up the SRAM RED eTap 2x11 system to do sequential shifting?

No. Sequential shifting is one of the Enhanced Shift modes available for AXS systems. With RED eTap, the rider always controls the front derailleur.

Note: SRAM AXS controllers that are paired to 11-speed SRAM Red eTap derailleurs will not be configurable in the AXS app.